Retuning the body

Retuning the body

To transform the standard of care for chronic disease with non-invasive wearable neuromodulation therapies.

About Cala Health®

Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company’s wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation, and its vertically integrated commercial model is reshaping the delivery of prescription therapies. Cala Health’s lead product, Cala Trio™, is the only non-invasive prescription therapy for essential tremor. New therapies are under development in neurology, cardiology and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.

Company Story

Cala Health

About Cala Trio™

A breakthrough, individualized therapy for hand tremors in people with essential tremor.

Learn More

Cala Health Trio

In The News

Electricity as Medicine: Lux Capital's Josh Wolfe and Cala Health CEO Renee Ryan

Lux Capital Managing Partner and Co-Founder Josh Wolfe visits the headquarters of Lux portfolio company Cala Health in Burlingame, California and has a conversation with CEO Renee Ryan. You'll get an inside look at how Cala is empowering people with chronic disease.

Cala Health named A GOLD WINNER of the 2020 Edison Awards

Cala Trio therapy took the GOLD award for Diagnostics & Disease Treatment in the Medical Device/Dental category. Among the nomination entries comprising the best products, services, and businesses in innovation for the year 2020, Cala Trio was chosen as a winner by a panel of over 3,000 leading business executives from around the world.

Cala Health Applauded by Frost & Sullivan for Revolutionizing the Essential Tremor Market with its Body-worn Neuromodulation Therapy, Cala Trio™

Based on its recent analysis of the North American essential tremor (ET) treatment market, Frost & Sullivan recognizes Cala Health, Inc. with the 2019 North American Technology Innovation Award for its Cala Trio™, a prescription-only, wrist-worn device.

Game Changing Startups 2020

We highlight 2020's emerging trends to watch and high-momentum startups with world-changing potential. The past few decades have seen unprecedented levels of innovation, especially in what Peter Thiel calls the world of “bits,” or software, internet, and mobile technology.

Cala Health aims to restore functionality to essential tremor patients with wearables

For Kate Rosenbluth, founder and chief scientific officer of Cala Health, and Renee Ryan, its CEO, the painting is a reminder of why they do their work every day: to restore functionality — and even bring back the joy of life — for the estimated 7 million people in the U.S. living with the condition.

Current Therapy Cala Health Takes on Neurological conditions with a novel approach- by reverse engineering the body's nervous system.

I sat in an occupational therapy office with electrodes stuck to my right hand, playing a game of Connect Four. Or at least I attempted to play, unsuccessfully, as I had for the last 10 weeks.

Cala Health: Medtech as Bioelectric Medicine

Wearables are a hot topic in medtech circles today. But are they really medtech? Cala Health’s Trio device for treating essential tremors underscores the challenges and opportunities that wearables represent when compared to traditional medical devices.

It looks like a smartwatch, but this new device is helping people with tremors

People who live with tremors know it can impact every part of your life. Essential tremor is a nervous system disorder that causes involuntary shaking. It can be hard to write legibly, and even eat or drink without spilling.

Individualized, Non-invasive therapy for essential tremor- An interview with Kate Rosenbluth of Cala Health

When I was an Innovation Fellow, doing needs finding with my team, I met a man whose hands shook so badly that he could no longer write a letter to his wife or drink a coffee with a friend. He had a severe form of a debilitating disorder called essential tremor.

Watch Like Device Helps Tremors

Doctors from the University of Arkansas for Medical Sciences in Little Rock are looking into new ways to reduce and hopefully stop essential tremors for patients.

Treatment With Neuromodulation Device Improves Essential Tremor in Clinical Trial

In the PROSPECT study, a wrist-worn neuromodulation device Cala Trio by CalaHealth, Inc. provided symptomatic relief for essential tremor (ET).

Daily Use of Cala Trio Device Effectively Eases Hand Tremors, Trial Reports

Using Cala Health’s non-invasive therapeutic device Cala Trio for 40 minutes twice daily effectively helped to reduce hand tremors within three months, results from a clinical study show.

Record Clinical Trial Enrollment Made Possible by IETF and Their Members

Patient recruitment is usually the biggest challenge in conducting clinical trials. Thanks to the International Essential Tremor Foundation and their members, CalaHealth recently enrolled the largest therapeutic essential tremor study in record time.

Essential Tremor Symptoms, Severity Improved With Cala Trio Neuromodulation Device

Results of the landmark PROSPECT trial of the Cala Trio, a wrist-worn wearable neuromodulation device for essential tremor (ET), suggest that the device is safe and effective for the reduction of hand tremor in individuals with ET.

Six New HealthTech Founders Join the StartUp Health Platform

StartUp Health has been the most active investor in health innovation companies in 2019. And we’re not slowing down. Meet the latest Health Transformers to join our family.

Meet the Team

Renee Ryan
Renee Ryan Chief Executive Officer
Kate Rosenbluth, PhD
Kate Rosenbluth, PhD Founder & Chief Scientific Officer
Kristie Burns
Kristie Burns Chief Marketing Officer
Bobby Thomas
Bobby Thomas VP of Digital

Join the Team

Cala Health believes our success is based on diversity of people, teams and thinking. We offer all employees the tools, training and mentoring they need to succeed. Our selection process is driven by the key requirements for the role rather than bias or discrimination on the basis of a candidate’s sex, gender identity, age, marital status, veteran status, non-job-related disability/handicap or medical condition, family status, sexual orientation, religion, color, ethnicity, race or any other legally protected classification.

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Problem-Solving Mindset

Building a new category of therapies requires breakthrough thinking. Intense curiosity drives us to discover and design life-changing solutions.

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Collaborative Culture

Talented people thrive in passionate, inclusive teams where every team member matters. We inspire each other to make the impossible possible.

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Building the Future

We are delivering innovative therapies at the cutting-edge of technology and neuroscience. We believe non-invasive electrical medicines will change the face of healthcare.


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